Most of us take anabolic steroids solely as a means to build muscle and improve athletic performance. Indeed, according to various sources, about 80-90% of professional athletes, bodybuilders, weightlifting and powerlifting, taking anabolic steroids. These drugs have become a mandatory attribute of the youth sports movement in the world. From 30 to 60% of boys practicing in athletic clubs regularly use anabolic steroids. With their irregular distribution is a struggle every possible means. In some countries, young people bullied “terrible” consequences of taking anabolic steroids, in others – their distribution and use is punishable by law. Great attention is paid this topic and the media, especially during competitions and championships. The fact that anabolic steroids – a drug that showed high efficacy and safety in a wide range of diseases.
The mechanism of action of anabolic steroids is not similar to the action of peptide hormones. Once in the blood, steroid molecules are dispersed throughout the body, where they react with the cells of skeletal muscles, sebaceous glands, hair follicles, certain areas of the brain and some endocrine glands. Anabolic steroids are soluble in fats, so they can penetrate through the membrane of cells composed of fat; intracellular anabolic steroids interact (communicate) with the androgen receptors of the nucleus and cytoplasm. Activated androgen receptors transmit the signal inside the cell nucleus, resulting in a changed expression of genes or activate processes that send signals to other parts of the cell. The result is a stimulation of all kinds of nucleic acids and starts the process of formation of new protein molecules.
The effect of anabolic steroids on muscle growth due to the following mechanisms:
anabolic
reduced recovery time
decreases the effect of catabolic hormones (cortisol, etc.)
shift the differentiation of cells in the direction of the muscle, reducing the formation of fatty
acceleration of metabolic reactions, due to what is the disintegration of fat
The effects of anabolic steroids can be divided into two main categories: anabolic and androgenic.
Anabolic effects:
A significant increase in muscle mass (5.10 kg per month)
The increase in power rates
Increase stamina and performance
Increasing the number of red blood cells
Strengthening of bone
Decrease of fat reserves
Androgenic effects:
Masculinization
Virilization
Hypertrophy of the Prostate
Testicular atrophy
Loss of hair on his head, and the activation of growth on face and body
In bodybuilding are needed only anabolic effects. Currently under development steroids, which have a pronounced anabolic effect and low androgen. The index, which reflects the ratio is called an anabolic index. Currently, nearly all anabolic steroids have androgenic effects.
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